What is it about?

Napin, a major seed storage protein in rapeseed, mustard and Canola has been characterised, its amino acid structure, tertiary structure and sequence motifs that are thought to be responsible for allergenicity are mapped.

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Why is it important?

Napin has great molecular, proteomic, clinical importance due to its high potential as human food. Characterisation of the napin will give important insight into the protein structure, and epitope modelling will help to advance studies into allergenicity including the development of precise diagnostic screenings and therapies for this potential food allergy as well as the possible manipulation of napin levels in the seed by gene editing technology.

Perspectives

This study links the sequence motifs in napin with allergenicity with and indicates the way to improve rapeseed protein to utilise as a source of food.

Dr Mahmudur Rahman
Southern Cross Analytical & Research Services, Southern Cross University

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This page is a summary of: Identification, characterization and epitope mapping of proteins encoded by putative allergenic napin genes from Brassica rapa, Clinical & Experimental Allergy, May 2020, Wiley, DOI: 10.1111/cea.13612.
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