Endogenous lysophosphatidic acid (LPA1) receptor agonists demonstrate ligand bias between calcium and ERK signalling pathways in human lung fibroblasts

  • Endogenous ligand bias at the LPA1receptor
  • Afrah Sattikar, Mark R Dowling, Elizabeth M Rosethorne
  • British Journal of Pharmacology, January 2017, Wiley
  • DOI: 10.1111/bph.13671

What is it about?

The way in which different fatty compounds can cause effects in the body can be determined by their different profiles of signalling inside cells. Here we have explored how these profiles differ for a number of fatty compounds found naturally in the body.

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