What is it about?

This research presents a retrospective observational study analyzing trends in surgical interventions for benign prostate enlargement (BPE) within the UK National Health Service (NHS) in England, covering the period from April 2012 to November 2022. This study utilized Hospital Episode Statistics to track patients receiving their first surgical treatment for BPE, following them longitudinally to assess in-hospital and longer-term outcomes. Key findings indicate that less invasive treatments are associated with a reduced likelihood of in-hospital complications compared to the traditional transurethral resection of the prostate (TURP), although they may entail a higher risk of re-intervention within five years. This study highlights an increased uptake of minimally invasive procedures that offer shorter hospital stays and a lower risk of immediate complications, but their long-term efficacy remains variable. The analysis employed multivariable logistic regression and Kaplan-Meier analysis to explore the relationships between surgical modality and the odds of in-hospital complications and re-intervention risk, respectively. The findings support the shift towards less invasive treatments in the NHS, underscoring the need for consideration of long-term outcomes in surgical decision-making. This study emphasizes the utility of real-world data from routine administrative databases for evaluating surgical interventions on a national scale.

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Why is it important?

This study investigates the trends and outcomes of surgical interventions for benign prostate enlargement (BPE) within the UK National Health Service over a decade. The research is significant in providing real-world evidence on the effectiveness and risks associated with various surgical treatments, which is crucial for informed decision-making by patients, clinicians, and healthcare policymakers. As the prevalence of BPE increases with an ageing population, understanding the comparative benefits and drawbacks of these treatments is vital for optimizing patient care and resource allocation. Key Takeaways: 1. The research demonstrates that less invasive treatments for BPE, while associated with lower immediate complication rates and shorter hospital stays, may lead to a higher risk of re-intervention within five years compared to the traditional TURP procedure. 2. Findings reveal an increasing trend towards the adoption of minimally invasive surgical options within the NHS, reflecting a shift in treatment practices aimed at reducing short-term morbidity, although the long-term effectiveness of these options varies. 3. This study highlights the value of utilizing comprehensive hospital episode statistics to monitor surgical outcomes, providing empirical evidence to support healthcare decisions and potentially influencing future funding and policy directions in the realm of BPE treatment.

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This page is a summary of: Surgery for benign prostate enlargement in England: 10‐year retrospective study of 155 874 patients, BJU International, March 2025, Wiley,
DOI: 10.1111/bju.16713.
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