Outcomes of Artificial Urinary Sphincter Placement in Patients with Prior Male Sling

What is it about?

The study investigated the outcomes of artificial urinary sphincter (AUS) placement in patients with post-prostatectomy urinary incontinence (PPUI) with or without a prior male sling. The primary endpoint was to determine the proportion of patients who achieved social continence, defined as self-reported use of 0-1 pad/day. The secondary endpoints were device failure rates and device failure-free survival. The analysis included 210 patients, with 30 (14.3%) having had prior slings and 180 (85.7%) without prior slings. After AUS insertion, 80% of patients with prior slings and 76.7% of those without prior slings achieved continence (0-1 pad/day). There were six (20.0%) and 53 (29.4%) device failures in patients with and without prior slings, respectively. The median device failure-free survival was not reached in patients with prior slings and was 8.9 years in patients without prior slings (P = 0.048). The study found that the efficacy and safety of AUS in patients with prior slings are similar to those without. Prior sling is associated with a longer device failure-free survival. AUS remains a viable option in patients who have persistent PPI after prior slings. [Some of the content on this page has been created by AI]

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Why is it important?

The research investigates the outcomes of artificial urinary sphincter (AUS) placement in patients with post-prostatectomy urinary incontinence (PPUI) with or without a prior male sling. It is essential because it helps determine the efficacy and safety of AUS in patients who have had prior slings and provides information on device failure rates and failure-free survival. This information is critical for healthcare professionals to make informed decisions about the best treatment options for patients with PPUI. Key Takeaways: 1. AUS is effective in patients with and without prior sling use, with approximately 80% of patients in both groups achieving social continence after AUS placement. 2. The overall device failure rate was 28.1% during the 15-year follow-up period, and the median device failure-free survival was 9 years. Prior sling is associated with a longer device failure-free survival. 3. The continence rates were 80% for those with prior slings and 76.7% for those without prior slings, which are similar to those in previous series.