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What is it about?
The study reports on the first-in-human experience of using the LithoVue Elite TM ureteroscope to measure intrarenal pressure (IRP) during flexible ureteroscopy. A single-arm retrospective observational analysis was performed on 50 consecutive patients undergoing ureteroscopic lithotripsy with the LithoVue Elite TM system with pressure sensing capability. The median and maximum IRPs and relative cumulative time exceeding pre-defined IRP cut-off values were analysed. The study found that the IRP can now be routinely measured during ureteroscopy, with a median IRP of 28.5 mmHg and a maximum of 174 mmHg. The study also found that patients with Asian ethnicity, and those without pre-stenting or UAS use exhibited longer cumulative/total durations exceeding pre-defined IRP cut-off values.
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Why is it important?
This research is important because it is the first in-human experience using the LithoVue Elite TM ureteroscope, a novel pressure-sensing device that can measure intrarenal pressure (IRP) during flexible ureteroscopy. The study analyzed the median and maximum IRPs and relative cumulative time exceeding pre-defined IRP cut-off values during 50 consecutive patients undergoing ureteroscopic lithotripsy. Key Takeaways: 1. The LithoVue Elite TM ureteroscope is the first pressure-sensing device that can measure IRP during flexible ureteroscopy. 2. The median IRP of all cases was 28.5 mmHg, and the IRP remained at <60 mmHg during most of the time during flexible ureteroscopy cases. 3. Keeping the IRP below 40 mmHg may help prevent possible infectious complications, as pyelovenous/pyelosinus backflow occurs at this level.
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Read the Original
This page is a summary of: Retrospective first‐in‐human use of the LithoVue™ Elite ureteroscope to measure intrarenal pressure, BJU International, September 2023, Wiley,
DOI: 10.1111/bju.16173.
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