What is it about?

Eye-movement profiles, although well-known to be anomalous in psychiatric disorders, are shown in this paper to not explain the slow BRR trait in bipolar disorder (BD).

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Why is it important?

This negative finding provides further positive evidence for the trait's clinical diagnostic and endophenotype utility — which will be assessed through large-scale BRR phenotyping of genotyped cohorts (i.e., 10,000s with psychiatric disorders and in controls) — and genetic analyses including GWAS, polygenic risk score association with PGC (Psychiatric Genomics Consortium) disorders, gene-/pathway-based analyses and Mendelian randomization methods.

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This page is a summary of: Evidence that eye-movement profiles do not explain slow binocular rivalry rate in bipolar disorder: support for a perceptual endophenotype, Bipolar Disorders, July 2017, Wiley, DOI: 10.1111/bdi.12515.
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