What is it about?

By using a simplified upper airways model (set in different micro-ambient), we were able to simulate the amount of water that might be produced when placing a patient on HHHFNC devices.

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Why is it important?

Here are some of the major points: In the case of significant airway humidification as occurs with HHHFNC therapy, less respiratory tract water loss is expected, or even a positive balance, as we believe may occur according to the present results Even relatively small amounts of water accumulated might count as mechanically and/or physiologically significant for newborn infants in whom the respiratory systems have very small volumes An extrinsic factor of water burden over the preterm lung should be considered in relation to an intrinsic factor of poor water management, originating in prematurity itself and a continuum of lung injury and repair (e.g.: evolving bronchopulmonary dysplasia


Writing this article was a great pleasure as it has co-authors with whom I have had long standing collaborations. In fact, it was my first - first author experience - which turned out to be great.

Eran Reiner

Read the Original

This page is a summary of: Using heated humidified high‐flow nasal cannulas for premature infants may result in an underestimated amount of water reaching the airways, Acta Paediatrica, December 2020, Wiley,
DOI: 10.1111/apa.15675.
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