What is it about?

The study was performed at nine Japanese medical institutions for patients who had experienced an active CSC episode. Patients with CSC who received corticosteroids and had bilateral disease, chronic manifestation, non-intense fluorescein leakage on fluorescein angiography or a relatively thinner CRT should be closely monitored to identify whether they are at high risk of recurrence.

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Why is it important?

We herein integrated and analysed clinical and imaging data from a multicentre study to investigate the poten- tial risk factors for recurrence in patients with CSC. Increasing our awareness of the risk factors for recurrence of CSC has pivotal relevance for early detection, intensive treatment and promoting disease management.


CSC recurrence can be predicted by a history of corticosteroid use, bilateral disease, chronic manifestation, non-intense fluorescein leakage and the initial CRT. Among these five risk factors, the five-factor combination model provided significantly stronger predictability than that with the single-factor model. Therefore, early recognition of the possible risk factors is essential for preventing CSC recurrence, and patients at high risk for recurrence require careful treatment and frequent surveillance to avoid deterioration of vision.

zhou xiaoyin
Hyogo Ika Daigaku

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This page is a summary of: A multicentre study of the risk factors associated with recurrence of central serous chorioretinopathy, Acta Ophthalmologica, May 2022, Wiley, DOI: 10.1111/aos.15194.
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