What is it about?

Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by microangiopathy, extensive fibrosis and autoantibody production. SSc patients with cerebral involvement and multiple macrovascular stenosis have been rarely described. We herein report a case of cerebral infarction and severe stenosis of the internal carotid artery and coronary artery associated with SSc

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Why is it important?

It is generally believed that microvascular disease is the hallmark of systemic sclerosis. Macrovascular involvement is not initially considered as a feature of SSc, but its mortality is high, which should not be ignored.


I hope this article can make us realize that systemic sclerosis patients may be complicated with multiple macrovascular stenosis.

Lanjing Wang

Read the Original

This page is a summary of: Systemic sclerosis with cerebral infarction and severe stenosis of internal carotid artery and coronary artery: A case report, International Journal of Rheumatic Diseases, August 2022, Wiley,
DOI: 10.1111/1756-185x.14427.
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