What is it about?
Hermetia illucens-3 (HI-3), an active insect antimicrobial peptide extracted from Hermetia illucens larvae, exerts antibacterial and anticancer activity. Except its antibacterial and anticancer activity, we have showed that HI-3 exerts its anti-inflammatory effect by inhibiting the expression of proinflammatory cytokines and the activation of p65 and IκB, which indicated that HI-3 could be a promising therapeutic medicine for inflammation.
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Why is it important?
It was expceted that HI-3 could be a promising therapeutic medicine for inflammation.
Perspectives
The results would provide the target of anti-inflammation of antimicrobial peptide.
Qiang Xia
Zunyi Medical University
Read the Original
This page is a summary of: Antimicrobial peptide HI‐3 from
Hermetia illucens
alleviates inflammation in lipopolysaccharide‐stimulated RAW264.7 cells via suppression of the nuclear factor kappa‐B signaling pathway, Microbiology and Immunology, November 2022, Wiley,
DOI: 10.1111/1348-0421.13031.
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