What is it about?

External electrostatic fields (ESF) are the man-made ecological factor, which are everywhere. The understending of the biological aplication of these fields is in importance. The purpose of this paper was to reveal the possible changes in membrane physical parameters, such as surface charge, xi-potential and molecular interactions of membrane components due to the in vitro and in vivo influences of ESF.

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Why is it important?

The understanding of the mechanisms underlying the biological effects of ESF influence would allow us to avoid the health effects of ESF and, at the same time, it will be possible to use these fields in medicine and biotechnology. In this paper,we have shown that the in vivo influence of ESF leads to the intermolecular reconstructions and decrease of the positive charged groups in membrane surface layer. At the same time, the increases of the negative charged groups of membrane proteins after the field influence, is revealed. The charge redistribution in membranes due to the in vitro influence of ESF is observed.

Perspectives

Our studies in revealing the membrane mechanisms of ESF biological effects are in progress.

Dr Gohar Vardan Sahakyan
Yerevan State Medical University Named after Mkhitar Heratsi

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This page is a summary of: External electrostatic field induced changes of rat erythrocyte membranes, COMPEL The International Journal for Computation and Mathematics in Electrical and Electronic Engineering, July 2015, Emerald,
DOI: 10.1108/compel-09-2014-0240.
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