What is it about?
The article describes the new structure of a heterocyclic compound containing pyrimidoquinoline framework, which has potential bioactivity, such as antimicrobial, anticancer, antimalarial, anti-inflammatory, and antihistaminic.
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Why is it important?
The reported crystal structure is new and belongs to the pyrimidoquinoline family, known for its wide range of biological activities. As such, this compound is promising in pharmaceutical research for developing new drugs. The article also provides detailed crystallographic data, which helps understand the compound's structure and supports the design of more effective drugs. This contributes to ongoing efforts in creating better therapeutics targeting various diseases.
Perspectives
Crystallography plays a crucial role in drug design by revealing how molecules are structured, aiding in potential drug optimization.
Dr. Adesola Abimbola Adeleke
University of KwaZulu-Natal Faculty of Science and Agriculture
Read the Original
This page is a summary of: 10-(4-Chlorophenyl)-4-[(4-fluorophenyl)amino]-5-phenyl-5,8,9,10-tetrahydropyrimido[4,5-b]quinolin-6(7H)-one, IUCrData, September 2025, International Union of Crystallography,
DOI: 10.1107/s2414314625007758.
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