What is it about?
It is about finding consistent biological 3D structures in heavily contaminated electron microscopy data sets without using any prior knowledge
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Why is it important?
It can be used to advance knowledge across many biomedical disciplines
Perspectives
I am just happy to be back developing algorithms for cryo-EM after a few years break
Hans Elmlund
NIH
Read the Original
This page is a summary of: Probabilistic single-particle cryo-EM ab initio 3D reconstruction in SIMPLE, Acta Crystallographica Section D Structural Biology, July 2025, International Union of Crystallography,
DOI: 10.1107/s2059798325005686.
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