What is it about?

A novel thermostable aldo–keto reductase Tm1743 from Thermotoga maritima was overexpressed with an N-terminal His6 tag, purified and co-crystallized with NADP+.

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Why is it important?

Degradation of the N-terminal vector-derived amino acids was identified by Western blot and Mass Spectrometry analysis.

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This page is a summary of: Crystallographic analysis of a novel aldo-keto reductase fromThermotoga maritimain complex with NADP+, Acta Crystallographica Section F Structural Biology Communications, June 2015, International Union of Crystallography,
DOI: 10.1107/s2053230x15009735.
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