What is it about?
The [4]pseudorotaxane of b-cyclodextrin (b-CD) with coffee chlorogenic acid (CGA) has been reported for the first time in CD inclusion complexes. The atomistic and thermodynamic insights of the trimodal and dimeric b-CD–CGA inclusion complexes are gained through single-crystal X-ray diffraction combined with DFT calculation.
Featured Image
Why is it important?
After over two decades of controversy on the b-CD–CGA inclusion complex, X-ray crystallography sheds light on the true binding mode in which the two symmetry-related CGA molecules are enclosed in a formed dimeric b-CD cavity. CGA is stabilized in the b-CD cavity through intermolecular H-bonding, hence improving its antioxidant property.
Perspectives
For CD inclusion complexes, this paper on coffee chlorogenic acid is one among several papers on tea catechins and olive polyphenols. These functional foods are commonly available in our kitchen. Now, this work is finally done.
Thammarat Aree
Chulalongkorn University
Read the Original
This page is a summary of: Inclusion complex of β-cyclodextrin with coffee chlorogenic acid: new insights from a combined crystallographic and theoretical study, Acta Crystallographica Section C Structural Chemistry, January 2019, International Union of Crystallography,
DOI: 10.1107/s2053229618016741.
You can read the full text:
Contributors
The following have contributed to this page
