What is it about?
The interactions and structure of a protein that regulates decisions in DNA replication.
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Why is it important?
The structure of the coiled coil domain of this this protein, holds details that were difficult to predict by its sequence alone, and the biophysical properties of the molecule help explain its function in cells.
Perspectives
The structure of GemC1 and the discussion of its complex with Geminin, can help to better understand its properties in DNA replication.
Dr Anastassis Perrakis
netherlands cancer institute
Read the Original
This page is a summary of: The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins, Acta Crystallographica Section D Biological Crystallography, October 2015, International Union of Crystallography,
DOI: 10.1107/s1399004715016892.
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