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Why is it important?

Previously, I demonstrated that PCA based unsupervised FE to miRNA-mRNA expression in multiple cancers. In this paper, using matched data set, I show that identified pairs are associated with the expected negative correlations between mRNA and miRNA.

Perspectives

I have used PCA based unsupervised FE to multiple bioinformatic problems. I demonstrated that this methodology can be applied to identification miRNA-mRNA expression using gene expressions.

Professor Y-h. Taguchi
Chuo Daigaku

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This page is a summary of: microRNA-mRNA interaction identification in Wilms tumor using principalcomponent analysis based unsupervised feature extraction, June 2016, Cold Spring Harbor Laboratory Press,
DOI: 10.1101/059295.
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