How brain networks communicate

What is it about?

The brain can be parceled into spatially segregated networks; however, this raises the question, how do distinct networks talk to each other? In this review, we show how propagation of very slow spontaneous activity acts to facilitate cross-network communication.

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Why is it important?

It is now widely accepted that the general network organization of the brain is extremely stable, including in the setting of pathology such as psychiatric illness. However, it is very likely that although networks are intact, altered brain function results from altered communication between networks. Thus, understanding how networks communicate may provide an essential key to better understanding a host of neural pathologies.