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Ion channels are gates in the membrane of a cell that allow charged atoms to pass between the cell and its environment. They are involved in important functions like the generation of heartbeats and nerve impulses. Molecular "hardware" constraints allow them to work only at several pre-defined activity levels called modes. In order to enable the cell to respond to external signals, channels must switch between these modes.

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This page is a summary of: Statistical analysis of modal gating in ion channels, Proceedings of the Royal Society A Mathematical Physical and Engineering Sciences, April 2014, Royal Society Publishing,
DOI: 10.1098/rspa.2014.0030.
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