What is it about?
An evolutionary mathematical used to model tumor metabolism changes. Ideas from evolutionary game theory model cells cooperation within a tumor. It could identify the ideal time to disrupt metastatic cancer cell cooperation and make a tumor more vulnerable to anti-cancer drugs.
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Why is it important?
The work underscores the importance of studying the environment in which tumor cells evolve and develop a metabolic symbiosis. Pharmaceutical companies could potentially disrupt the symbiotic cellular development and stunt tumor growth.
Read the Original
This page is a summary of: Critical transitions in a game theoretic model of tumour metabolism, Interface Focus, June 2014, Royal Society Publishing,
DOI: 10.1098/rsfs.2014.0014.
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Resources
Researchers use game theory in battle against cancer
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“Game Theory” Model Reveals Vulnerable Moments for Metastatic Cancer Cells' Energy Production
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