What is it about?
Identification of Clostridium difficile genotypes associated with recurrent C difficile infection (RCDI).
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Why is it important?
The presence of the binary toxin gene and tcdC SNPs C184T and A117T were found to strongly predict RCDI. The presence of both tcdC SNPs and the binary toxin gene significantly increased the risk of RCDI, which might warrant longer antibiotic courses to eradicate the infection.
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This page is a summary of: Single Nucleotide Polymorphisms of the tcdC Gene and Presence of the Binary Toxin Gene Predict Recurrent Episodes of Clostridium difficile Infection, Annals of Surgery, August 2014, Wolters Kluwer Health,
DOI: 10.1097/sla.0000000000000469.
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