What is it about?

This publication describes the isolation and characterization of a bacteriophage virus targeting the bacterial pathogen Shigella flexneri.

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Why is it important?

This work not only highlights the identification of a pathogen-specific bacteriophage, but also demonstrates the use of a novel, human-specific model of the gastrointestinal epithelium that can be used as a therapeutic candidate screening platform.

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This page is a summary of: Bacteriophage Therapy Testing against Shigella flexneri in a Novel Human Intestinal Organoid-Derived Infection Model, Journal of Pediatric Gastroenterology and Nutrition, November 2018, Wolters Kluwer Health,
DOI: 10.1097/mpg.0000000000002203.
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