What is it about?

We found that 8 characteristics of osteoarthritis knee pain were related the central nervous system (brain or spinal cord). These characteristics were anxiety; depression; other painful areas; how one thinks about pain; how pain affects attention to a task; sleep disturbance; fatigue; and pain that feels tingly or electrical in nature.

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Why is it important?

Through selecting 8 questions representing these characteristics we have created a new questionnaire to help identify people whose pain is driven by the central nervous system. Clinicians can use this questionnaire to help identify individuals whose central pain mechanisms play a significant role in driving pain. It will help determine whether current or new treatments that target central pain mechanisms, might improve a specific individual’s knee pain.


For large scale surveys (of big populations or large studies of people), this questionnaire will be very useful for helping researchers work out what mechanisms might be causing pain.

Dr Daniel McWilliams
University of Nottingham

Read the Original

This page is a summary of: Traits associated with central pain augmentation in the Knee Pain In the Community (KPIC) cohort, Pain, June 2018, Wolters Kluwer Health, DOI: 10.1097/j.pain.0000000000001183.
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