COVID-19 associated acute kidney injury

What is it about?

This paper presents a comprehensive review of the incidence, mechanisms, risk factors, and clinical outcomes of acute kidney injury (AKI) in patients with COVID-19. It explores how SARS-CoV-2 directly and indirectly contributes to kidney damage through pathways such as viral entry into renal cells, cytokine storm, endothelial dysfunction, and coagulopathy. The study also examines the impact of pre-existing conditions, the role of supportive care, and the implications of AKI on overall prognosis in COVID-19 patients. By synthesizing current evidence, the paper provides valuable insights to guide early recognition, risk stratification, and management of AKI in the context of COVID-19.

Featured Image

Photo by Evergreens & Dandelions on Unsplash

Photo by Evergreens & Dandelions on Unsplash

Why is it important?

Acute kidney injury (AKI) is a frequent and serious complication in COVID-19 patients, associated with increased morbidity, mortality, and long-term health consequences, yet its mechanisms and optimal management strategies remain incompletely defined. Understanding the link between SARS-CoV-2 infection and kidney injury is essential for improving patient outcomes, especially in critically ill individuals. This study is important because it synthesizes current evidence on the pathogenesis, risk factors, and clinical impact of COVID-19–associated AKI, offering critical guidance for early detection, prevention, and tailored therapeutic interventions to reduce kidney-related complications and improve survival.

Perspectives