Histopathologic Features Predicting Recurrence in Small Renal Masses

What is it about?

This study explores the histopathological features of a contemporary series of small renal masses (SRMs) and investigates parameters that could predict their pathological nature, metastatic potential, and recurrence potential. The majority of SRMs were malignant, with a higher incidence among those with a diameter of >2 cm. The mean tumor diameter was significantly larger in patients with malignant masses. The study emphasized the importance of histopathological features and treatment modalities in predicting malignant recurrence. The results provide valuable information for treatment decision-making, considering the patient's age, comorbidities, tumor characteristics, imaging features, and pathohistological diagnosis.

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Why is it important?

The research is important because it investigates the histopathological features of a contemporary series of small renal masses (SRMs) and explores parameters that could predict their pathological nature, metastatic potential, and recurrence potential. This study helps clinicians and researchers better understand SRMs and make more informed decisions about treatment options, leading to improved patient care and outcomes. Key Takeaways: 1. The majority of treated neoplasms were malignant, but their incidence was low among SRMs with a diameter of <2 cm. 2. The study emphasizes the importance of histopathological features and treatment modalities in predicting malignant recurrence. 3. Tumor size, Fuhrman grade, stage, nodal and distant metastasis status, tumor localization, and treatment modality are characteristics significant for tumor recurrence. 4. Proper treatment decisions should be considered after assessment of the patient's age, comorbidities, tumor characteristics, imaging features, and pathohistological diagnosis.