What is it about?
A critique of a randomised trial inadequately analysed for prognostic factors.
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Why is it important?
Randomising subjects in a trial does not necessarily randomise the disease under study.
Perspectives
The reliance solely on the randomization procedure in a clinical trial, without scrutiny of the prognostic factors involved in melanoma or any other cancer, provides a false security of "reliable clinical science" and can obscure the true results and outcome of a particular treatment. Such practice should be avoided.
Dr Spyros Retsas
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This page is a summary of: Adjuvant treatment with vindesine for metastatic melanoma: in response to the study of Eigentler et al. (2008), Melanoma Research, April 2009, Wolters Kluwer Health,
DOI: 10.1097/cmr.0b013e328324589e.
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