What is it about?
This and article describes the effect of long term use of parentral pamidronate in children with osteogenesis imperfecta and the consequences of long term osteoclastic inhibition with the resultant non traumatic stress fractures.
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Why is it important?
The long term use of Intravenous pamidronate is actually associated with increased fracture risk.
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Read the Original
This page is a summary of: Unusual Femur Stress Fractures in Children With Osteogenesis Imperfecta and Intramedullary Rods on Long-term Intravenous Pamidronate Therapy, Journal of Pediatric Orthopaedics, January 2016, Wolters Kluwer Health,
DOI: 10.1097/bpo.0000000000000552.
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