Propofol based sedation does not increase rate of perforation during colonoscopy

S. Amornyotin, U. Prakanrattana, U. Kachintorn, W. Chalayonnavin, S. Kongphlay
  • European Journal of Anaesthesiology, June 2010, Wolters Kluwer Health
  • DOI: 10.1097/00003643-201006121-00118

Propofol based sedation does not increase rate of perforation during colonoscopy

What is it about?

Sedation related colonoscopic perforation (CP) has been under much debate. Our aim was to assess and compare the CP rate during colonoscopy by using sedation with or without propofol adjuvant.

Why is it important?

There were no significant differences in age, sex, weight, ASA physical status and duration of procedure between the two groups. In group A, nine patients (0.16%) suffered from perforation, and two of them died. In group B, one patient (0.20%) had the CP. No difference in the CP rate with respect to receiving sedation with or without propofol adjuvant was noted (p=0.852). The most common CP site was sigmoid colon. The characteristics of patients and sedative agents used in perforated patients in both groups were not significantly different.

Perspectives

Somchai Amornyotin
Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University

Our data showed that colonoscopy under propofol based sedation did not increase the perforation rate. Additionally, colonoscopy is relatively safe and effective when performed by physicians in training. Serious complications are uncommon.

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http://dx.doi.org/10.1097/00003643-201006121-00118

The following have contributed to this page: Somchai Amornyotin