Statins in adult patients with HIV

  • Protocol for a systematic review and network meta-analysis
  • Leonardo Roever, Elmiro Santos Resende, Angélica lemos Debs Diniz, Nilson Penha-Silva, João Lucas O’Connell, Paulo Fernando Silva Gomes, Hugo Ribeiro Zanetti, Anaisa Silva Roerver-Borges, Fernando César Veloso, Thiago Montes Fidale, Antonio Casella-Filho, Paulo Magno Martins Dourado, Antonio Carlos Palandri Chagas, Sadeq Ali-Hasan-Al-Saegh, Paulo Eduardo Ocke Reis, Rogério de Melo Pinto, Gustavo B. F. Oliveira, Álvaro Avezum, Mansueto Neto, André Durães, Rose Mary Ferreira Lisboa da Silva, Antonio José Grande, Celise Denardi, Renato Delascio Lopes, Nitesh Nerlekar, Shahab Alizadeh, Adrian V. Hernandez, Giuseppe Biondi-Zoccai
  • Medicine, April 2018, Wolters Kluwer Health
  • DOI: 10.1097/md.0000000000010116

Statins in adult patients with HIV: Protocol for a systematic review and network meta-analysis.

What is it about?

Patients with HIV have been found to suffer from lipid abnormalities, including elevated levels of total and LDL-cholesterol as well as triglyceride levels. Abnormal lipid levels are associated with an increased risk of developing cardiovascular diseases, which are significant causes of mortality among the general population. Therefore, the objective of the current study is to conduct a systematic review with network meta-analysis to compare the effects of statins classes on HIV patients.

Why is it important?

Abnormal lipid levels are associated with an increased risk of developing cardiovascular diseases, which are significant causes of mortality among the general population. Therefore, the objective of the current study is to conduct a systematic review with network meta-analysis to compare the effects of statins classes on HIV patients.

Perspectives

Professor Paulo Eduardo Ocke Reis
Universidade Federal Fluminense

Ethics approval was not required for this study because it was based on published studies. The results and findings of this study will be submitted and published in a scientific peer-reviewed journal. The evidence will determine which combination of interventions are most promising for current practice and further investigation.

Read Publication

http://dx.doi.org/10.1097/md.0000000000010116

The following have contributed to this page: Dr Nilson Penha-Silva and Professor Paulo Eduardo Ocke Reis