What is it about?
1. Rag1-/-Rag2-/-Il2rg-/Y (SD-RG) rat is a severely immunodeficient model lacking mature T, B and NK cells. 2. SD-RG rats can support fast growth of human lung cancer xenografts, while retaining the histopathological features of the original tumor. 3. SD-RG rats serve as a novel model for oncology research.
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This page is a summary of: A novel immunodeficient rat model supports human lung cancer xenografts, The FASEB Journal, January 2019, Federation of American Societies For Experimental Biology (FASEB),
DOI: 10.1096/fj.201800102rr.
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