What is it about?

How collagen plays roles in bone metabolism? Collagen just a structual protein for bone tissues? We disclosed a new mechanism and role for collagen in bone.

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Why is it important?

Collagen can induce the osteoblastic activity.

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This page is a summary of: Insulin receptor substrate-1 time-dependently regulates bone formation by controlling collagen I 2 expression via miR-342, The FASEB Journal, September 2016, Federation of American Societies For Experimental Biology (FASEB),
DOI: 10.1096/fj.201600445rr.
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