What is it about?

Findings suggest that airway epithelial cells release exosome-like vesicles and that these structures may be involved in diverse physiological processes in airway biology, including innate mucosal defense against flu viruses

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Why is it important?

Our functional analyses indicate that these structures may have a role in innate defense against respiratory pathogens that bind sialic acid, such as human influenza virus. This a novel proposed function for exosomes/vesicles and will lead to a greater understanding of the role of the exosomes in airway biology and innate defense.

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This page is a summary of: Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense, The FASEB Journal, June 2009, Federation of American Societies For Experimental Biology (FASEB),
DOI: 10.1096/fj.08-119131.
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