Silica-induced initiation of circular ZC3H4 RNA/ZC3H4 pathway promotes the pulmonary macrophage activation

Xiyue Yang, Jing Wang, Zewei Zhou, Rong Jiang, Jie Huang, Lulu Chen, Zhouli Cao, Han Chu, Bing Han, Yusi Cheng, Jie Chao
  • The FASEB Journal, June 2018, Federation of American Societies For Experimental Biology (FASEB)
  • DOI: 10.1096/fj.201701118r

What is it about?

As shown in this study, circZC3H4 RNA/ZC3H4 mediates macrophage activation. This study reveals a novel function for circZC3H4 RNA/ZC3H4 and provides a possible mechanism for the inflammatory reaction process observed in some pulmonary diseases associated with fibrosis.

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