Insulin receptor substrate-1 time-dependently regulates bone formation by controlling collagen I 2 expression via miR-342

  • Y. Guo, C.-Y. Tang, X.-F. Man, H.-N. Tang, J. Tang, F. Wang, C.-L. Zhou, S.-W. Tan, Y.-Z. Feng, H.-D. Zhou
  • The FASEB Journal, September 2016, Federation of American Societies For Experimental Biology (FASEB)
  • DOI: 10.1096/fj.201600445rr

IRS-1 and Collagen regulate bone metabolism

What is it about?

How collagen plays roles in bone metabolism? Collagen just a structual protein for bone tissues? We disclosed a new mechanism and role for collagen in bone.

Why is it important?

Collagen can induce the osteoblastic activity.

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http://dx.doi.org/10.1096/fj.201600445rr

The following have contributed to this page: Hou-De Zhou