What is it about?
ACS, is a Th1-biased immune disease and that statins as immunomodulatory agents ameliorate cardiovascular diseases.
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Why is it important?
Statins are well established in all patients at risk of any type of major cardiovascular events. The impact of statin treatment in patients with wide spectrum of cholesterol levels has raised the question about the beneficial effects of statins beyond cholesterol lowering. This Editoral provides a new aspect of statins as immunomodulatory agents.
Perspectives
There is growing evidence that coronary heart disease, particularly ACS, is a Th1-biased immune disease and that statins as immunomodulatory agents ameliorate cardiovascular diseases.
Kazunori Shimada
Juntendo University
Read the Original
This page is a summary of: T helper 1/T helper 2 balance and HMG-CoA reductase inhibitors in acute coronary syndrome: statins as immunomodulatory agents?, European Heart Journal, April 2006, European Society of Cardiology,
DOI: 10.1093/eurheartj/ehl376.
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