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The activity of the nuclear factor-Y (NF-Y) transcription factor is restricted to proliferating cells in vitro. Authors engineered transgenic mice that enabled bioluminescence imaging of NF-Y activity in every area of the body. Authors visualized areas of proliferation, and highlight for the first time a role of NF-Y activity in hepatocyte proliferation during liver regeneration in vivo.
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This page is a summary of: Molecular imaging of nuclear factor-Y transcriptional activity maps proliferation sites in live animals, Molecular Biology of the Cell, February 2012, American Society for Cell Biology (ASCB),
DOI: 10.1091/mbc.e12-01-0039.
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Molecular imaging of nuclear factor-Y transcriptional activity maps proliferation sites in live animals
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