The gp91 phox Component of NADPH Oxidase Is Not a Voltage-gated Proton Channel

  • Thomas E. DeCoursey, Deri Morgan, Vladimir V. Cherny
  • The Journal of General Physiology, November 2002, Rockefeller University Press
  • DOI: 10.1085/jgp.20028704

What is it about?

We summarize the arguments against the hypothesis that one component of NADPH oxidase functions as a proton channel.

Why is it important?

This was early in the decade-long controversy about whether gp91phox (a component of NADPH oxidase) was also a proton channel. We know now that it is not.

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The following have contributed to this page: Professor Thomas E DeCoursey