What is it about?
In this study, we analyzed the splicing patterns of a Brachypodium splicing factor, Bd-SCL33, during infection with seven viruses.
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Why is it important?
We found dynamic and conserved changes in Bd-SCL33 splice variants during virus infections. Many of the splice variants contain pre-mature termination codons and encode truncated proteins, that could inhibit the activity of full-length Bd-SCL33 protein in a dominant negative manner.
Perspectives
Modulation of Bd-SCL33 activity could represent a means to control genome-wide changes in splicing landscapes during biotic stress.
Kranthi Kiran Mandadi
Texas A&M University
Read the Original
This page is a summary of: Characterization of SCL33 splicing patterns during diverse virus infections in Brachypodium distachyon, Plant Signaling & Behavior, July 2015, Taylor & Francis,
DOI: 10.1080/15592324.2015.1042641.
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