What is it about?

These synthesized bis(triazolothiadiazinyl coumarin) compounds were evaluated for broad spectrum of antiviral activity. Among all the tested compounds, compound 5f exhibited antiviral activity against H1N1 virus.

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Why is it important?

The molecular docking studies of Bis coumarinyl bis triazolothiadiazinyl ethane derivatives compounds against H1N1 neuraminidase enzyme were performed. The binding affinity and binding values were compared with standard drugs.

Perspectives

Our findings show that the binding affinity and binding values were compared with standard drugs.

RAJESH KESHARWANI

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This page is a summary of: Bis coumarinyl bis triazolothiadiazinyl ethane derivatives: Synthesis, antiviral activity evaluation, and molecular docking studies, Synthetic Communications, May 2018, Taylor & Francis,
DOI: 10.1080/00397911.2018.1455871.
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