The interaction between vitamin C and bone health: a narrative review

Alberto Falchetti, Roberta Cosso
  • Expert Review of Precision Medicine and Drug Development, May 2018, Taylor & Francis
  • DOI: 10.1080/23808993.2018.1482211

vitamin C roles in osteoporosis and fracture prevention.

What is it about?

A narrative review on potential roles of vitamina C on bone health

Why is it important?

Since uncertainties, limitations, and open questions on the role of vitamin C in human skeletal health still remain, indications or recommendations on vitamin C supplementation to improve bone health, or prevent osteoporosis, are not currently appropriate.


Endosmet, Villa Donatello, Private Hospital, FLorence, Italy

The future studies have to clarify the effect of vitamin C on several different bone parameters and a deepest comprehension of protective mechanisms in abnormal redox and acid–base state is necessary. Further clinical studies on vitamin C effects on bone health should be needed, both on bone-quantity/quality and reduction of fracture risk, to obtain significant clinical data with reliable statistical analysis.

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The following have contributed to this page: Dr. ALBERTO FALCHETTI