Attenuation of Sulfite-Induced Testicular Injury in Rats by Zingiber officinale Roscoe

  • Akbar Afkhami Fathabad, Shahnaz Shekarforoush, Maryam Hoseini, Zahra Ebrahimi
  • Journal of Dietary Supplements, August 2017, Taylor & Francis
  • DOI: 10.1080/19390211.2017.1349233

Attenuation of sulfite injury

What is it about?

sulfite salts including sodium metabisulfite (SMB) are widely used as preservatives in foods and pharmaceutical agents. The results of our study showed that spermatogenesis, epididymal morphometry, and sperm parameters were affected by SMB. There was a significant increase in MDA level and a significant reduction in the activities of glutathione peroxidase (GPx), glutathione reductase (GR), and catalase (CAT) in the SMB-treated rats compared to the control. Ginger treatment of SMB-exposed rats significantly increased testosterone level and the number of different spermatogenic cells. The level of MDA reversed to the control levels and the activities of GPx and GR were significantly increased when SMB was coadministered with ginger extract.

Why is it important?

The mentioned effects might be very important for reproductive health because processed and packaged foods have become a convenient choice for today’s busy families.


Shahnaz Shekarforoush
Islamic Azad University

I hope this article makes people think more about the type of foods for having.

Read Publication

The following have contributed to this page: Shahnaz Shekarforoush