What is it about?

The development of light-inducible systems has allowed us to control single signalling molecules with incredible precision. Now, we can combine this precision to the discovery of drug-target interactions, by activating or inhibiting certain pathways that are the expected drug targets. We can use these systems to rescue signalling and thus pin-point the actual targeting molecule.

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Why is it important?

This is a new point of view to increase the accuracy and understand drug targeting. Moreover, it can speed up the long and tenuous drug discovery pipeline.


This is a very cleaver approach to solve an existing problem

Professor Adolfo Rivero-Muller
Uniwersytet Medyczny w Lublinie

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This page is a summary of: Optogenetics in cancer drug discovery, Expert Opinion on Drug Discovery, February 2018, Taylor & Francis, DOI: 10.1080/17460441.2018.1437138.
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