Green Synthesis and Antibacterial Activity of Cu-Ag Bimetallic Oxide Nanocomposites

What is it about?

This research focuses on the green synthesis of bimetallic oxide nanocomposites using aqueous crude leaf extract of Eichhornia crassipes by the hydrothermal method. The study investigates the antibacterial potential of the synthesized CuO/Ag2O/Ext (2) and CuO/Ag2O NCPs (3) against four human pathogens: E. coli, K. pneumonia, S. aureus, and S. epidermides. The results show that compound (2) exhibits better antibacterial performance than compound (3) against the tested bacteria using the disc diffusion method. The study also characterizes the synthesized materials using XRD, SEM, FTIR, UV-Vis, and TGA techniques, confirming the nano-size structure and bioactive compounds present in the E. crassipes extract. The low-cost, easily scalable preparation of these materials and their potential for enhancing antibacterial activity make them useful for pharmaceutical industrial development.

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Why is it important?

This research study focuses on the green synthesis of bimetallic oxide nanocomposites using the aqueous crude leaf extract of Eichhornia crassipes. The study aims to investigate the antibacterial potential of the synthesized CuO/Ag2O/Ext (2) and CuO/Ag2O NCPs (3) against four human pathogens bacteria, namely Staphylococcus aureus, Staphylococcus epidermides, Escherichia coli, and Klebsiella pneumonia. The research is important because it highlights the potential use of plant extracts in the synthesis of bimetallic nanocomposites, which can be utilized in various applications such as antibacterial agents, catalysis, and sensing devices. This study contributes to the field of green chemistry by promoting sustainable and eco-friendly methods of synthesis. Key Takeaways: 1. The study successfully synthesized CuO-Ag2O bimetallic oxide nanocomposites using the hydrothermal method with the aqueous crude leaf extract of E. crassipes. 2. The antibacterial activity of the synthesized nanocomposites (2) and (3) was assessed against four human pathogens bacteria, and compound (2) showed better antibacterial performance than compound (3). 3. The XRD technique confirmed the nano-size structure of (2) and (3) with a size of 33.41 nm and 28.22 nm, respectively. 4. The study provides insights into the use of natural and bioactive compounds found in plant extracts for the synthesis of bimetallic nanocomposites, which can be further explored for various applications in the fields of medicine, catalysis, and sensing devices.