What is it about?

This study investigates the viability of a drug-eluting stent to minimise granulation tissue growth, a problem in current stent therapy, and facilitate local chemotherapy administration to reduce side effects.

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Why is it important?

Incorporating paclitaxel into a silicone matrix for future use in a tracheobronchial stent was investigated. Drug release from silicone was observed and is a promising avenue for future treatments of central airway pathologies.

Perspectives

I hope this article helps assist for others to come up with innovative solutions in treating lung cancer using emerging technologies in 3D-printing, and drug-elution capabilities.

Jesse Xu
University of Sydney

Read the Original

This page is a summary of: Paclitaxel-eluting silicone airway stent for preventing granulation tissue growth and lung cancer relapse in central airway pathologies, Expert Opinion on Drug Delivery, August 2020, Taylor & Francis,
DOI: 10.1080/17425247.2020.1811224.
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