What is it about?
we show that mitochondria and cells leak electrons into the network of connective tissues, thus rendering connective tissues a function of an ROS-related electric channel. The new fate of mitochondrial electrons that we reveal and the role of connective tissues as a ROS/superoxide electric channel will not only upend the current understanding about reactive oxygen species, but also radically challenge molecular interaction-based concepts of signal transduction and metabolism regulation, demonstrating a promising clue to an electric approach to understanding biology.
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Why is it important?
We traveled a profound distance, theoretically speaking, to elucidate the mechanism of ROS-fluorescent distribution in mice, rats and monkeys and its biological significance, defining the importance of mitochondrial-leaked electrons and redefining the role of connective tissues. These observations, we believe, will result in transformational progress in the many studies of biology.
Perspectives
a promising clue to an electric approach to understanding biology.
Jingke Guo
Zhejiang Gongshang University
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This page is a summary of: Visualising reactive oxygen species in live mammals and revealing of ROS-related system, Free Radical Research, October 2019, Taylor & Francis,
DOI: 10.1080/10715762.2019.1677902.
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