What is it about?

Raman imaging represents just a modest fraction of all research and clinical microscopy, because it is either slow or requires high irradiance levels. Here, we report Raman imaging at rapid rates, low irradiance, and increased magnification by deploying non-diffracting beams and by harnessing the particle nature of light .

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Why is it important?

Raman imaging exhibits an enormous potential in scientific or clinical settings. Our findings will enable tapping into this potential and accelerate related investigations, including single cell metabolic analyses in cancer and strain engineering.


Very grateful for the funding from the U.S. Department of Energy

Andreas Vasdekis
University of Idaho

Read the Original

This page is a summary of: Video-rate Raman-based metabolic imaging by Airy light-sheet illumination and photon-sparse detection, Proceedings of the National Academy of Sciences, February 2023, Proceedings of the National Academy of Sciences,
DOI: 10.1073/pnas.2210037120.
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