What is it about?

Time signals in the form of periodic environment stimuli is everywhere in our life. We study the networks of information flow in populations of neural cells as the external time signals vary. Our work aim to answer how do cells communicate, and how does this communication allow many different cells to respond collectively to a global stimulus -- all without deliberately calibrating the noisy clocks of individual cells.

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Why is it important?

Understanding how a group of cells cooperatively processes an environmental signal is an essential step to decoding the organizing principles of multicellular organisms. Decoding such systems will lead to a better understanding of a diverse range of physiological processes, offering insights into disease mechanisms and treatment.


Our brains have amazing skills in measurement and computation. How does these capabilities scale to the minimal systems, such as a monolayer of neural cells? It is fascinating to define and study cognitive processes in simple neuron cell systems so we can better understand the information processing powers of living systems.

Bo Sun
Oregon State University

Read the Original

This page is a summary of: Temporal signals drive the emergence of multicellular information networks, Proceedings of the National Academy of Sciences, September 2022, Proceedings of the National Academy of Sciences,
DOI: 10.1073/pnas.2202204119.
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