What is it about?
We identified the major vault protein (MVP) as a key mediator between our immune system and bacterial communication - thereby advancing our understanding of how certain bacteria are able to aid our immune system to suppress tumor formation.
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Why is it important?
This work provides a unique perspective into how the immune system senses and reacts to bacterial signaling molecules through MVP, and this interaction appears to result in a decreased ability of tumor cells to gain resistance against our immune system
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This page is a summary of: Immunoediting role for major vault protein in apoptotic signaling induced by bacterial
-acyl homoserine lactones, Proceedings of the National Academy of Sciences, March 2021, Proceedings of the National Academy of Sciences, DOI: 10.1073/pnas.2012529118.
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