Improving biosystem performance by mixing myosin isoforms
What is it about?
We use a computational model to combine and simulate the force-velocity-energy properties of myosin motor proteins driving muscles and nanotechnologies. We show that certain combinations of two myosins working together have unique and advantageous properties in comparison to systems with only one type of myosin.
Why is it important?
The project is unique because we combine myosin types and use computational models to test myosins at a faster rate than biological experiments could accomplish. We then validate the high performing biosystems predicted computationally with laboratory experiments.
The following have contributed to this page: Professor Paul Egan