What is it about?
Synchronization is the emergence of order in a population of connected oscillators. We optimise the timing and shape of external stimulation to push the entire system towards a state of disorder. We demonstrate that we can establish and stabilise desynchronization with the continuous application of those optimized pulses.
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Why is it important?
Some neurological disorders (e.g. Parkinson's disease) might originate in an over-pronounced synchronization in specific brain areas. With Deep Brain stimulation (DBS) techniques, implanted electrodes can stimulate those areas. So far, continuous high-frequency stimulation has proven effective and is an established medical treatment. With this work, we want to take a step towards laying a theoretical ground for future adaptive and energy-saving stimulation protocols.
Read the Original
This page is a summary of: Optimizing charge-balanced pulse stimulation for desynchronization, Chaos An Interdisciplinary Journal of Nonlinear Science, January 2022, American Institute of Physics, DOI: 10.1063/5.0070036.
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