Finding the best timing to push a synchronized system towards disorder

What is it about?

Synchronization is the emergence of order in a population of connected oscillators. We optimise the timing and shape of external stimulation to push the entire system towards a state of disorder. We demonstrate that we can establish and stabilise desynchronization with the continuous application of those optimized pulses.

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Photo by Brett Jordan on Unsplash

Photo by Brett Jordan on Unsplash

Why is it important?

Some neurological disorders (e.g. Parkinson's disease) might originate in an over-pronounced synchronization in specific brain areas. With Deep Brain stimulation (DBS) techniques, implanted electrodes can stimulate those areas. So far, continuous high-frequency stimulation has proven effective and is an established medical treatment. With this work, we want to take a step towards laying a theoretical ground for future adaptive and energy-saving stimulation protocols.